Evidence profile
Ara-290 (10 mg Vial)
Cibinetide has been studied in sarcoidosis-associated small-fiber loss. The results need a clear distinction between nerve imaging and symptom relief.
01
Product identity
Identity and formulation must be matched to the clinical study material.
02
What has been studied
Primary human trial
A nerve-fiber endpoint
- Population or model
- 64 people with sarcoidosis-associated small-fiber loss and neuropathic pain
- Study route or material
- Subcutaneous in a 28-day controlled study
In a 64-person, 28-day trial, one active-dose group improved corneal nerve-fiber area. The reported placebo-corrected pain comparison was not statistically significant. The imaging result should not be described as proven general pain relief.[1]
03
Evidence limits
Long-term patient benefit and broader neuropathy indications remain unestablished in this selected source review.
The reviewed sources do not establish patient instructions for this product. No dose, cycle, preparation method or administration schedule is provided here.
04
Formulation and handling evidence
Exact product identity, strength and current stock-lot linkage.
Manufacturer-supported formulation, container, diluent compatibility and storage information.
A compatible diluent, prepared-solution stability and container/device compatibility must be supported for the exact formulation. The diluent manufacturer’s instructions do not supply a universal storage period for every dissolved substance.[3]
05
Approval context
This profile has not established Canadian authorization of the linked research product.[2]
06
Sources and review scope
- Cibinetide phase 2b study in sarcoidosisPrimary human trial · Abstract and original methods passage · Checked 2026-09-08
- Health Canada: unauthorized injectable peptide productsRegulatory advisory · Fresh Health Canada advisory read, including product/DIN and RUO-label limits · Checked 2026-09-09
- Hospira/Pfizer: bacteriostatic water manufacturer informationManufacturer information; US presentation · Fresh manufacturer page, relevant compatibility/storage/supply passages · Checked 2026-09-09
- Amino Labs: ARA-290 | 10mgSupplier listing; identity reference · Exact heading, SKU, form and supplier URL from the full catalogue capture; not stock-lot authentication · Checked 2026-09-09
This is a selected-source evidence summary. It is not a systematic review, formal certainty grade or qualified clinical sign-off. Study dates and source-check dates are distinct.